Is your skin looks young?

Three easy ways to test your skin's firmness

PINCH

Gently pinching the skin on your cheeks, do you feel a pulling sensation and that the skin is becoming thinner?

PUSH

Gently lifting the skin on your cheeks, does the skin sag?

SMILE

When you smile in the mirror, do fine lines or wrinkles appear around your cheeks?

What is the universal cause of skin aging?

From the age of 20, 1% of collagen is lost per year so skin feels less firm as our body’s collagen declines naturally 14.

Age 35

Up to 15% of collagen loss14.

Age 45

Up to 25% of collagen loss14.

Age 55

Up to 35% of collagen loss14.

Collagen is a key component of youthful skin6-9

Collagen is the most common protein in the body and acts as the skin’s support structure. Collagen provides your skin with:6,8,10-13

Firmness

Elasticity

Structure

Why use Sculptra®?

Sculptra® Injectable poly-L-lactic acid firming the skin, restores elasticity promotes collagen autopoiesis4-6Sculptra® stimulates production of your skin’s own collagen from within6,8,15,16.

5 Key Aspects of Sculptra®

Made the "Sculptra® Way" with the unique formulation containing PLLA-SCA17,18

Manufacturer and Manufacturer process is US FDA-approved19,20

Proven to stimulate collagen type I 67%6

Progressive, natural-looking21results that last over 25 months22,23

Approved in over 40 countries9

Sculptra® 's proprietary method for collagen regeneration

Progressive, Natural-Looking results that last at least 25 months*7,22,23

STUDY DESIGN AND OUTCOME
* Randomized, evaluator-blinded, parallel-group, multicenter study
*Subjects reveived injectable PLLA-SCA (n=116) or collagen (n=117) injections (1-4 visits, 3-week intervals)
* Wrinkle Assessment Scale scores were calculated at screening, week 3, months 3, 6, 9, and 13 (injectable PLLA-SCA or collagen groups) and months 19 and 25 (injectable PLLA-SCA group)
* Conclusion: Injectable PLLA-SCA provides well-tolerated, effective, and long-lasting (up to 25 months) nasolabial fold wrinkle correction

* p<0.001 vs baseline.
† p<0.001 vs human collagen.
± Only subjects treated with Sculptra® (n=106) were included in long-term surveillance phase.

Sculptra® gradually rebuilds the foundation of the skin*6

STUDY DESIGN AND OUTCOME
* Exploratory single-arm, open-label study.
* 14 healthy subjects received injectable PLLA-SCA.
* Biopsies at 3, 6 and 12 months.
* Conclusion: Significant stimulation of collagen type I after the treatment with PLLA-SCA.

Significant effect

of patients reported sustained improvement in skin firmness.
0 %
of patients reported sustained improvement in skin radiance (glow).
0 %
of practitioners agreed that the jawline was still enhanced.
0 %

High patient satisfaction for more than 25 months7,27

of patients said they had natural-looking results⁷
0 %
of patients felt better about themselves⁷
0 %

patients would recommend Sculptra to a friend⁷

0 /10
of patients thought they looked younger⁷
0 %
of patients felt more confident⁷
0 %
of patients would have the treatment again⁷
0 %

Skin that feels like you again

Full forehead; Check lift; Lighten nasolabial folds

Actual patient. Treatment with 3 vials of Sculptra® in 3 sessions. Individual results may vary.

Smooth temple & jawline; Full cheeks; Lighten nasolabial folds

Actual patient. Treatment with 3 vials of Sculptra® in 3 sessions.

* Individual results may vary.

The key to progressive, natural-looking

Firm, radiant skin for a natural-looking, rejuvenated appearance7.

Long-lasting improvement with no return to baseline for at least 25 months*7,22,23.

Proven safety profile based on extensive scientific and clinical data26,27.

High patient satisfaction for at least 25 months+4,7 .

* 86% of patients continued to show IGE scores of improvement up to 25 months after the last treatment.
+ 81% of patients rated their results as improved to excellent improvement” at 25 months.

555 Massage

5 times a day for 5 minutes after each Sculptra®  session. The massage* helps the ingredients to be more evenly distributed over the treated area, the treatment effect is more ideal.

Precautions
‧After the treatment, it is important to focus on moisturizing.
‧Gently press from the center of the face outward.
‧Repeat the massage on each area 3-5 times.

Q&A

Is Sculptra® right for me?

If you want subtle yet noticeable and long-lasting results, Sculptra® is right for you to refresh your look, improve the facial wrinkles and restore volume.

How many vials are required for a full treatment?

On average, a full Sculptra® treatment comprises 3 sessions, which are spaced 4-6 weeks apart, and around 3-6 vials are required. Of course it varies from person to person.

When will I see results from Sculptra®?

Sculptra® stimulates natural collagen growth, the noticeable results can be seen starting at week 3. It takes 6-9 months to see the optimal results, which last up to 25 months.

What are the possible side effects of treatment with Sculptra®?

Side effects of Sculptra® may include temporary discomfort, redness, bruising, bleeding, itching or swelling.

Where should I go for Sculptra® treatment?

You should contact a qualified practitioner who had completed a Sculptra® official training program and choose an authorized treatment centre that provides genuine products.

Authorized Treatment Certificate

Before your treatment, please verify that the medical center has been granted a Sculptra® Authorized Treatment Centre Certificate by Galderma HK Limited every six months. Ensure that you are treated by a qualified and certified professional doctor to receive the most comprehensive protection!

Reference
1. Kim J. Arch Aesthetic Plast Surg. 2014;20(2):97–103.2. Kerscher M, et al. Dermatol Surg. 2008;34(5):720–726.
3. Ribé A, et al. J Cosmet Laser Ther. 2011;13(4):154–161.
4. Bohnert K. et al. Plast Reconstr Surg. 2019;127(4):1684-1692.
5. Mest DR, Humble G. Dermatol Surg. 2006;32(11):1336-1345.
6. Goldberg D, et al. Dermatol Surg. 2013;39(6):915–922.
7. Fabi S, et al. Eectiveness and safety of correction of cheek wrinkles using biostimulatory poly-L-lactic acid
injectable implant – Clinical study data up to 24 months. Poster presented at the International Master Course on
Aging Science (IMCAS) World Congress, 26–28 January 2023, Paris, France
8. Galderma. A patient’s guide to treatment with SCULPTRA®. 2021. Available from:
https://www.galderma.com/us/sites/default/les/2021-12/Patient_Brochure_Sculptra_US_1.pdf
9. Galderma Receives FDA Approval for New SCULPTRA® Label, Offering More Options to Aesthetic Partners.
Galderma. 2021. Available from:
https://www.galderma.com/news/galderma-receives-fda-approval-new-sculptra-label-offering-more-options-aest
hetic-partners
10. Noguchi A, Djerassi D. Chapter 15 – Amino Acids and Peptides: Building Blocks for Skin Proteins, Editors: Tabor
A, Blair RM, In Personal Care & Cosmetic Technology, Nutritional Cosmetics, William Andrew Publishing, 2009,
Pages 287–317.
11. Shoulders MD, Raines RT. Ann Rev Biochem. 2009;78:929–958.
12. Aziz J, et al. Skin Pharmacol Physiol. 2016;29(4):190–203.
13. Farage MA, et al. Adv Wound Care (New Rochelle). 2013;2(1):5–10.
14. Shuster S, et al. Br J Dermatol. 1975;93:639–643.
15. Marchado Filho CD, et al. Surg Cosmet Dermatol. 2013;5(4):345–350.
16. Lacombe V. Facial Plast Surg. 2009;25(2):95–99.
17. Asius J, et al. Inventors. US patent US 7,731,758 B2.2010.
18. Morgan P, et al. Product Manufacturing Process for Poly-L-lactic acid (PLLA-SCA). Poster presented at the
International Master Course on Aging Science (IMCAS) World Congress, 26–28 January 2023, Paris, France.
19. Pre-market Approval (PMA) (fda.gov).

HK-SCU-2400020 / July-2024