As we age, our skin loses fat, collagen, and other important elements that provide facial volume and support. We also start to see the formation of lines, wrinkles, and folds that can contribute to us looking older.

Define your own look

It's not only about smoothing the lines, wrinkles, and folds that come with age. Restylane products can also be used to help you achieve your personalized signature look by creating lift, structure, and volume.

Why use Restylane®?

Restylane®products contain a clear gel formulation of HA that is specifically designed to act like your body’s own naturally produced hyaluronic acid to give you the most individualized and natural-looking results8-13

5 Key Aspects of Restylane®

High performance that lasts

Fillers from the Restylane® range achieve results that last up to 24 months, depending on the product used and area treated*15 .

The closest to natural HA

Closest to your skin's own HA for individualized and natural-looking results3,4 .

A trusted product

Restylane® pioneered the original HA filler over 27 years ago and has been used in more than 65 million treatments worldwide in a diverse range of skin colors, tones, and types**+

Enhances your natural expression

Restylane® products work to enhance your face's natural movement for youthful-looking results8-13 .

A high level of treatment satisfaction

99% of patients would recommend Restylane® treatment to a friend14 .

* A second treatment (retreatment) was performed at 12 months in the same areas with the same products. Touch-up was allowed 1 month after both treatments.
** Restylane injectable gel was first approved for marketing and sale in September 1996 in the EU.
† Based on a Restylane publications analysis conducted in June 2021. Sources include a published post-marketing safety study of 638 patients and a retrospective analysis of adverse event reports encompassing 406,000 patients.

The versatility of Restylane® technologies is designed to give you individualized, natural-looking results that last8-13

Two complementary technologies to help achieve the look you want.

NASHA®

NASHA, Non-Animal Stabilized HyaluronicAcid

・A firm gel for precise and pronounced lifting and structure*,**,16−18.

・The closest to natural HA gel technology on the market3.4.

・Trusted by healthcare practitioners for over 27 years+5.

OBT™

OBT, Optimal Balance Technology

・A softer gel demonstrates flexibility from all angles16,19‍.

・Resilience to dynamic movement3.

・Resistance to compression and ability to stretch

* Product integration was assessed in an ex vivo human skin model using histological methods.
** The firm gel structure of NASHA prevents distribution into the surrounding tissue after injection, enabling targeted product integration and precision.

For bespoke, natural-looing results

The world’s most diverse range of fillers and skinboosters
Each and every product in our range of fillers and skinboosters is individually engineered for a different purpose, so that you can create a look tailored to each patient

Ultimate projection

Offers the highest projection and lift without volumizing, providing strong definition with precision8.

Versatile support

A firm gel in small particle that fills lines and wrinkles, providing versatile support9.

Subtle definition

A moderately soft and flexible gel that offers subtle definition and flexible support to enhance contour10.

Effortless volume

A moderately soft gel with larger particle size for volumizing with subtle projection, replacing volume loss, restoring natural contours and creating fullness11.

Kissable lips

A soft and flexible gel to plump, soften and naturally enhance lips, restoring shape and improving texture12.

Flexible refinement

Offers smooth tissue integration and the most flexible support for softening and filling fine lines13.

Significant effect

of patients agree that the immediate improvement was achieved after treatment²⁸.
0 %
of patients have an average satisfaction of 98%²⁹.
0 %
of patients agree that their results were natural³⁰.
0 %

Durable and visible full-face augmentation

Perceived improvement in facial appearance by subject and physician are high throughout 24 months14,15.

Results

Q&A

Why should I choose Restylane®

Restylane® is made in Sweden and offers the most diverse range of hyaluronic acid filler treatments with NASHAR® and OBT™ technology to meet your aesthetic needs.8−13

Is there any side effects for Restylane®?

Restylane®  is safe to use and is rare to induce severe side-effects. The common post-treatment reactions are skin redness, swelling, itching or pain, etc. These reactions usually disappear within a week after the treatment.

How long does a Restylane® treatment last?

Restylane®  is long-lasting but not permanent. A recent study showed that Restylane®  can last up to 24 months.14,15

Can Restylane®  be used with other aesthetic treatments?

Yes, Restylane®  works well with other aesthetic treatments to enhance the overall treatment result.

What should I pay attention to after the treatment?
After Restylane®  treatment, you can resume your normal activities. For the first 2 weeks, avoid exposure to excessive heat, e.g. sauna and hot springs. Also, please avoid massaging the treatment area and put on make up at least 1 day after the treatment.
Who is qualified to administer Restylane®  treatments?

You should contact a qualified practitioner who had completed a Restylane®  official training program and choose an authorized treatment centre that provides genuine products.

Authorized Treatment Certificate

Before your treatment, please verify that the medical center has been granted a Restylane®  Authorized Treatment Centre Certificate by Galderma HK Limited every six months. Ensure that you are treated by a qualified and certified professional doctor to receive the most comprehensive protection!

Reference
1. FDA Summary of safety andeffectiveness data. https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfpma/pma.cfm?id=P040024
2. Restylane ‡I AP37 199679A VEHER*.
3. Ohrlund A. J Cosmet Dermatol.2018;8:47-54.
4. Kablik J, et al. Dermatol Surg.2009;35 Suppl 1:302-12.
5. Data on File MA-55607.
6. Data on file MA-57232.
7. Data on file. MA-34483.
8. Data on file. QMS-4933. (Lyft)
9. Data on file. QMS-4706. (Restylane)
10. Data on file. QMS-8662. (Defyne)
11. Data on file. QMS-8665. (Volyme)
12. Data on file. QMS-8668. (Kysse)
13. Data on file. QMS-8633. (Refyne)
14. Andriopoulos B, et al. Presented at:AMWC Monte Carlo, Monaco. 2019.
15. Huang SH, et al. J Drugs Dermatol.2020;19:836-42.
16. Gregario Get al. Clin Cosmet InvestigDermatol 2022;15: 681-690.
17. Huang S and Tsai T. J Drugs Dermatol2020;19(9):836-842.
18. Lundgren Bet al. J Drugs Dermatol2018; 17(9): 982-986.
19. Talarico S, et al. Dermatol Surg.2015;41:1361-9.
20. RESTYLANE® SKINBOOSTERSTM Vital EUIF.
21. RESTYLANE® SKINBOOSTERS™M Vital LightEU IFU.
22. RESTYLANE® VOLYMETM EU IFU.
23. RESTYLANE® LYFT™M EU IFU.
24. RESTYLANE® EU IFU.
25. RESTYLANE® DEFYNE™M EU IFU.
26. RESTYLANE® REFYNETM EU IFU.
27. RESTYLANE® KYSSE TM EU IFU.
28. Swift A et al. Clin Cosmet InvestigDermatol 2017;10:229-238.
29. Data on file. MA-48544.
30. Rzany B, Cartier H, Kestemont P, etal. Dermatol Surg. 2012;38:1153-1161.
31. Data on file. MA-39680; Data on file.MA-40221; Data on file. MA-39613 HK-RES-2400032 / July-2024